Ketamine induced renal fibrosis in a ketamine addition rat model
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چکیده
منابع مشابه
Mesenchymal stem cells protect against the tissue fibrosis of ketamine-induced cystitis in rat bladder
Abuse of the hallucinogenic drug ketamine promotes the development of lower urinary tract symptoms that resemble interstitial cystitis. The pathophysiology of ketamine-induced cystitis (KC) is largely unknown and effective therapies are lacking. Here, using a KC rat model, we show the therapeutic effects of human umbilical cord-blood (UCB)-derived mesenchymal stem cells (MSCs). Daily injection ...
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Sir, Ketamine is a noncompetitive antagonist of the N-methyl-D-aspartate (NMDA) receptor. It is widely used as a dissociative anesthetic and is also used as an adjunct in pain management, particularly in opioid-tolerant patients. It blocks calcium channels and depresses sodium channel function as well as having anticholinergic effects. It inhibits the re-uptake of the catecholamines and may hav...
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ژورنال
عنوان ژورنال: Urological Science
سال: 2017
ISSN: 1879-5226
DOI: 10.1016/j.urols.2016.12.004